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Many wounds that fail to respond to traditional wound care and become chronic (greater than six months duration) may benefit from the application of platelet rich plasma (PRP).  Wounds are complex problems for the clinician as many different variables affect the outcome of treatment.  Vasculature, diet, pre-existing conditions (e.g. diabetes) all have an impact on how wounds heal.  We know that certain proteins, growth factors, are required for the body to heal itself.  We also know that platelets carry these potent growth factors necessary to begin tissue repair and regeneration at the wound site.  Once there, these growth factors can then initiate the healing cascade and begin the process of healing.  If, for whatever reason, these growth factors are not able to get to the site of injury due to poor vasculature the healing response may be limited.  We can now concentrate these special proteins outside the body and reintroduce them to the site of injury or wound and "supercharge" the start of the healing cascade.